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6.7 % of side-effects lead to serious adverse drug reactions (ADRs) 0.3% to 7% of all hospital admissions account for side-effects 30% to 60% of side-effects are preventable ...
Table 1. Examples of pharmacogenomic information in drug labels. Drug name ADR Genotype(s) test Label recommendation Ref. Adverse drug reactions (ADRs) are reported to be the fourth leading cause ...
Drug eruptions are adverse skin reactions to drugs that occur in about 3% of hospitalized people. They may resemble skin diseases very closely but generally fade away when the drug is withdrawn.
For example, if one study classified drugs on the basis of their pharmacologic properties (e.g., angiotensin-converting-enzyme [ACE] inhibitors or -blockers) and another study classified drugs by ...
Adverse drug reactions (ADRs) occur in around 20% of hospital inpatients and may be responsible for about 5%of hospital admissions (Pirmohamed et al, 2004; Mannesseet al, 1997). The risk is higher in ...
Pharmacogenomics is the study of the role of inherited and acquired genetic variation in drug response. 1 Clinically relevant pharmacogenetic examples, mainly involving drug metabolism, have been ...
For example, it estimated a 94.06% probability of hepatotoxicity for erythromycin, 88.44% for nephrotoxicity and 75.8% for hypertension in cisplatin.
More than a quarter of people on long-term medication experienced at least one adverse drug reaction over six years, according to a study of around 600 patients aged 70 and older in Ireland.
For example, it estimated a 94.06% probability of hepatotoxicity for erythromycin, 88.44% for nephrotoxicity and 75.8% for hypertension in cisplatin.
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