Introduction Patients with ischaemic mitral regurgitation (MR) have markedly increased cardiovascular mortality compared with those with primary MR. The sex-based prognosis of patients with ischaemic ...

Objective To explore if there is an increased cancer risk associated with folic acid supplements given orally. Design Systematic review and meta-analysis of controlled studies of folic acid ...

Introduction Fractures of the odontoid process frequently result from low impact falls in frail or older adults. These are increasing in incidence and importance as the population ages. In the UK, ...

Introduction Emicizumab effectively prevents bleeding in people with haemophilia A (PwHA), but is a burden for national healthcare budgets and consequently may limit access. According to the drug ...

Objective The attrition of medical students is an incredibly important problem feeding into healthcare workforce issues. This study seeks to explore the relationships between various mental health ...

Introduction Neck pain (NP) is a common musculoskeletal complaint and is increasing in prevalence. Current clinical practice guidelines and systematic reviews recommended conservative, pharmacological ...

Objectives In Japan, frailty is a major risk factor for requiring long-term care, especially among older adults aged 75 years or older (ie, late-stage older adults). Both physical and social factors ...

Introduction The Pain in Older People with Frailty Study is a mixed-method, co-design study, which aims to develop the content, implementation strategies, service and professional guidance to support ...

6 South London and Maudsley NHS Foundation Trust, London, UK Introduction Self-harm and suicide are major public health concerns among children and adolescents. Many risk and protective factors for ...

Objectives To explore the reporting barriers and related factors of medication errors among nurses in hospitals in China and provide a reference for safe medication management in hospitals. Design ...

1 NIHR CLAHRC for North West London, Chelsea and Westminster Hospital, London, UK 2 Department of Medicine, Imperial College London, Chelsea and Westminster Hospital, London, UK Setting A wide range ...

Introduction The increasing demand for long-term care (LTC) services in resource-constrained settings has highlighted significant gaps in both the quality of care and the quality of life (QoL) for ...