6.7 % of side-effects lead to serious adverse drug reactions (ADRs) 0.3% to 7% of all hospital admissions account for side-effects 30% to 60% of side-effects are preventable ...

Adverse drug reactions are a particular problem for older people. Age-related changes in how drugs are absorbed, distributed, metabolised and excreted as a result of, for example, reductions in liver ...

Adverse drug reactions (ADRs) occur in around 20% of hospital inpatients and may be responsible for about 5%of hospital admissions (Pirmohamed et al, 2004; Mannesseet al, 1997). The risk is higher in ...

Adverse drug reactions cause significant morbidity and mortality and incur a large cost to healthcare systems. Pharmacogenomics may help in the prediction and prevention of adverse reactions to drugs.

Table 1. Examples of pharmacogenomic information in drug labels. Drug name ADR Genotype(s) test Label recommendation Ref. Adverse drug reactions (ADRs) are reported to be the fourth leading cause ...

KEY POINTS Adverse drug reactions are common both in outpatient and inpatient settings. A meta-analysis of 39 prospective studies from American hospitals that was published in 1998 reported an ...

For example, it estimated a 94.06% probability of hepatotoxicity for erythromycin, 88.44% for nephrotoxicity and 75.8% for hypertension in cisplatin.

More than a quarter of people on long-term medication experienced at least one adverse drug reaction over six years, according to a study of around 600 patients aged 70 and older in Ireland.

Canada Adverse drug reaction database goes online CBC News · Posted: May 25, 2005 3:48 AM PDT | Last Updated: May 25, 2005 ...