Using the TriNetX database, investigators identified 256,523 new thiazide users aged 40 years or older, of whom 8.6% experienced a serum sodium level of 135 mmol/L or less within 6 months.

Messer said that thiazides may not be the first choice for every patient, however. She explained that “treatment must always be individualized,” because thiazide diuretics, like all ...

Current users of beta-blockers, thiazides, or thiazide-like diuretics were defined as those having received a prescription within 60 days prior to the date of fracture.

For those receiving and not receiving thiazide diuretics, the incidence of diabetes mellitus at 10 years after first stone event was 9.2 and 4.2 percent, respectively (hazard ratio [HR], 2.91; 95 ...

Patients who develop early hyponatremia after starting thiazide diuretics have a higher mortality risk than those with normal sodium levels, according to retrospective study data. “Hyponatremia ...

The use of thiazide diuretics was associated with a decreased risk of low energy fractures in people with Alzheimer's disease, a new study from the University of Eastern Finland shows. The ...

Mendelian Randomization Analysis of Genetic Proxies of Thiazide Diuretics and the Reduction of Kidney Stone Risk. JAMA Network Open, 2023; 6 (11): e2343290 DOI: 10.1001/jamanetworkopen.2023.43290 ...

Kidney stones affect nearly 10% of the global population. For more than three decades, thiazide diuretics, a common medication used for high blood pressure, have been the standard of care for ...

Genetic proxies of thiazide diuretics were significantly associated with 15% decreased odds of kidney stones, Adriana M. Hung, MD, MPH, of Vanderbilt University Medical Center in Nashville ...

By comparing the incidence of cholecystectomy among users of thiazide diuretics and those who did not use these drugs, the authors found a positive association between the use of thiazide ...

Thiazide diuretics are associated with an increased risk of hypokalemia. However, pharmacogenetic markers of thiazide-induced changes in serum potassium are not well studied. The aim of this study ...