DEAR DR. ROACH: I am a 52-year-old woman who was diagnosed with familial hypercholesterolemia in October 2024. I went through a cardiac workup for pain in my left arm and found this out.

But even for Crestor, the absolute risk of a serious problem was very low — 1 in 35,862. When side effects did occur, it tended to be within the first three months of use.

The primary end point in the Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin (SATURN) targeted a prespecified > 40 mm coronary segment.