At 52 weeks, avacopan plus rituximab is associated with a higher remission rate and improved recovery of renal function compared with prednisone taper plus rituximab, according to findings from a ...

Upon enrollment, patients were randomized 1:1 to receive 52 weeks of a twice-monthly injection of sarilumab 200 mg, plus 14 weeks of prednisone tapering, or placebo and 52 weeks of prednisone ...

Avacopan is superior to prednisone taper in preventing relapse in patients with antineutrophil cytoplasmic antibody-associated vasculitis at 1 year, and is at least as effective as steroids in ...

For patients with lung manifestations, remission rates were higher with avacopan vs a prednisone taper at both week 26 (73.2% vs 66.2%) and week 52 (67.6% vs 53.5%), respectively.

The ADVOCATE study was done to see if Tavneos was safe and effective for treating AAV, compared with prednisone, a corticosteroid. People in the study received either Tavneos or a prednisone taper ...

Results from a pilot study examining a shortened prednisone taper of 8 weeks’ length rather than 26 weeks suggest it may be possible to reduce patients' duration of exposure to glucocorticoids.

Based on baseline disease severity, subjects in our ongoing phase 2 study would have been expected to be treated with an initial prednisone dose of 0.75 mg/kg (equivalent to a mean dose of 62 mg ...

If a patient presents with symptoms of GCA but no ocular manifestations, administer oral prednisone 40-60 mg/day for approximately one month. 2,4 Therapy should be started immediately; do not wait ...

For example, in the multicenter Ritux 3 trial, which compared a tapered regimen of prednisone alone to rituximab combined with a shorter and lower-dose prednisone taper, complete response rates ...

I’d become an eating machine with a loathsome attitude on prednisone, so I decided to conduct my own taper of the drug. Four months after my allogeneic bone marrow transplant, I left the Stanford ...

A follow-up study presented at the MGFA 15th International Conference on Myasthenia and Related Disorders examined corticosteroid tapering among patients with myasthenia gravis who were currently ...

Rheumatology > Lupus Slow Steroid Tapering Succeeds in SLE — Flare rates were significantly lower with gradual withdrawal than with low-dose maintenance by Nancy Walsh, Contributing Writer ...