Wall Street's main indexes fell on Tuesday after U.S. President Donald Trump's latest plans for pharma tariffs renewed worries of the impact of a trade war, while some downbeat corporate results also weighed on investor sentiment.

Investors were feeling on edge Tuesday as uncertainty about President Donald Trump's trade policies looked set to drag down the blue-chip U.S. stock indexes. The Cboe Volatility Index, a widely followed fear gauge that tracks S&P 500 options contracts and trades under the ticker VIX,