Isaac Paredes hit a solo homer and Jose Altuve doubled twice with two RBIs to lead the Houston Astros over the Chicago White Sox 4-3.

Chicago White Sox starter Sean Burke allowed 7 runs in 3 2/3 innings during Wednesday’s 10-2 loss to the Houston Astros.

The Chicago White Sox have taken three of four from the Houston Astros so far this season, including Tuesday's 4-2 win. Ryan Gusto (3-3, 4.78) starts for Houston on Wednesday against Sean Burke (3-6,

Not only was the hit García’s third of the game, but the win on Saturday ensures that the Rangers will take the series over the White Sox. It also moves them within a game of .500 and only six games back of the American League West leaders Houston Astros.

Chicago White Sox starter Shane Smith allowed one run in six innings during Tuesday’s 4-2 win against the Houston Astros. The rookie lowered his ERA to 2.37.

Rookie Ryan Gusto, the beneficiary of the outpouring of offense, responded with his first quality start in the majors. Gusto threw six innings of two-run ball. Two relievers, Bryan King and Steven Okert, finished the win he started.

Luis Robert Jr. homered, Shane Smith pitched six effective innings and the Chicago White Sox beat the Houston Astros 4-2.

The Chicago White Sox (23-44) and the Houston Astros (36-30) play the second game of a 3-game series Wednesday. First pitch from Daikin Park in Houston is scheduled for 8:10 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the White Sox vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Houston tries to take the three-game series against the White Sox behind starter Framber Valdez who has won five last six starts.

Christian Walker homered among his three hits and had a season-high four RBIs to lead the Houston Astros over the Chicago White Sox 10-2 on Wednesday night. Jose Altuve added two hits to give him 2,300 in his career, joining Dodgers first baseman Freddie Freeman (2,342) as the only active players with at least 2,300.